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KMID : 0369819740040010119
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Jorunal of Korean Pharmaceutical Sciences
1974 Volume.4 No. 1 p.119 ~ p.124
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The Biopharmaceutical Studies on the Some Compounding Drugs ( Ⅲ ); Antipyritic Analgesic Effect on the Aminopyrine Combined with Atropine Sulfate by Writhing Method
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박영옥/Park YO
정기화/김재완/Chung KH/Kim JW
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Abstract
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The comparative studies were made on the analgesic antipyretic effects of aminopyrine used individually and combined with parasympathetic agents (atropine sulfate). The analgesic antipyretic effects were eximined by Writhing's method to the experimental groups(mouse), and the following effects were found : 1) The active intensity of aminopyrine by it's oral administration combined with atropine sulfate is as follows. Amiinopyrine 80 mg/kg combided with Atropine sulfate 0.005 mg/kg=Aminopyrine 100 mg/kg 2) The most active range of intensity of Atropine sulfate(adjuvant) by it's oral administration is as follows. Atropine sulfate $0.004{\sim}0.005\;mg/kg$ 수식 이미지.
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